CXCL16 Monoclonal antibody proteintech 60123-1-Ig
$449.00
In stock
SKU
60123-1-Ig
Small-inducible cytokine B16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, CXCL 16, C-X-C motif chemokine 16, C X C motif chemokine 16
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: Human And More (2) | Immunogen: CatNo: Ag4883 Product name: Recombinant human CXCL16 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 46-225 aa of BC017588 Sequence: GNGNEGSVTGSCYCGKRISSDSPPSVQFMNRLRKHLRAYHRCLYYTRFQLLSWSVCGGNKDPWVQELMSCLDLKECGHAYSGIVAHQKHLLPTSPPISQASEGASSDIHTPAQMLLSTLQSTQRPTLPVGSLSSDKELTRPNETTIHTAGHSLAAGPEAGENQKQPEKNAGPTARTSATV Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 273 aa, 30 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC017588 |
| Conjugate: Unconjugated | Gene Symbol: CXCL16 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 58191 |
| Application: Western Blot (WB) | RRID: AB_2086188 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II-induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow-derived fibroblast accumulation. |
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