NeutraKine? IL-6 Mouse McAb proteintech 69001-1-Ig
$339.00
In stock
SKU
69001-1-Ig
IL6, IL-6, 4G3E6, B-cell stimulatory factor 2, IFN-beta-2
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human And More (1) | Immunogen: Recombinant Protein Predict reactive species |
| Applications: IHC, IF, Neutralization, ELISA | Observed Molecular Weight: IL6 |
| Formulation: Sterile PBS | GenBank Accession Number: ENSG00000136244 |
| Conjugate: Unconjugated | Gene Symbol: AB_2882919 |
| Gene ID (NCBI): Unconjugated | |
| RRID: Lyophilized Powder | |
| Conjugate: Protein G purification | |
| Tested Reactivity: Human | Form: P05231 |
| Host / Isotype: Mouse / IgG1 | Background Information: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. This antibody can be used to neutralize the bioactivity of IL-6. |
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