Myocilin Monoclonal antibody proteintech 60357-1-Ig
$449.00
In stock
SKU
60357-1-Ig
GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, mouse, pig, rat | Immunogen: CatNo: Ag5492 Product name: Recombinant human MYOC protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 154-504 aa of BC029261 Sequence: EEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 57 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC029261 |
| Conjugate: Unconjugated | Gene Symbol: Myocilin |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4653 |
| Application: Western Blot (WB) | RRID: AB_2881465 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: human, mouse, pig, rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina (PMID: 9176893; 9169133). It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) (PMID: 21709622). |
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