Chk1 Monoclonal antibody proteintech 60277-1-Ig
$449.00
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60277-1-Ig
CHEK1, Chk1
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag0409 Product name: Recombinant human CHK1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 42-256 aa of BC004202 Sequence: MKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITI Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 54 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC004202 |
| Conjugate: Unconjugated | Gene Symbol: Chk1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1111 |
| Application: Western Blot (WB) | RRID: AB_2881396 |
| Dilution: WB : 1:1000-1:3000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: CHEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints, DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation(PMID:21389083). CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol(PMID:17276342). It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa, 44 kDa and 50 kDa. |
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