KU70,XRCC6 Monoclonal antibody proteintech 66607-1-Ig
$449.00
In stock
SKU
66607-1-Ig
KU70, XRCC6, 3C12D9, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag21301 Product name: Recombinant human KU70,XRCC6 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 307-609 aa of BC008343 Sequence: TGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHHYLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEELDDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFENPVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKVTKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELLEALTKHFQD Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, IF-Fro, FC (Intra), IP, CoIP, ChIP, ELISA | Observed Molecular Weight: 75 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC008343 |
| Conjugate: Unconjugated | Gene Symbol: KU70 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2547 |
| Application: Western Blot (WB) | RRID: AB_2881967 |
| Dilution: WB : 1:20000-1:100000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: X-ray repair cross-complementing protein 6(XRCC6)gene encodes subunit p70 of the p70/p80 autoantigen which has a role in DNA repair or transposition. DNA helicase II complex binds preferentially to fork-like ends of double-standed DNA in a cell cycle-dependent manner, which may be mediated by XRCC6. XRCC6/5 can form a heterdimer, which function as a regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA, and also it can stablize broken DNA ends and bringing them together. Otherwise, XRCC5/6 heterdimer together with APEX1 can negatively regulate of transcription. |
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