EPCAM/CD326 Monoclonal antibody proteintech 66316-1-Ig

$449.00
In stock
SKU
66316-1-Ig

 

EPCAM, 2A2D5, Adenocarcinoma-associated antigen, CD326, Cell surface glycoprotein Trop-1

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human And More (1) Immunogen: CatNo: Ag15393 Product name: Recombinant human EPCAM protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 24-264 aa of BC014785 Sequence: QEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICSKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSTCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQLDLDPGQTLIYYVDEKAPEFSMQGL Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, ELISA Observed Molecular Weight: 314 aa, 35 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC014785
Conjugate: Unconjugated Gene Symbol: EPCAM
Tested Applications: Positive WB detected in Gene ID (NCBI): 4072
Application: Western Blot (WB) RRID: AB_2881697
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. EpCAM may occur in distinct forms due to glycosylation. (PMID: 20837599; 19249674; 21576002; 22647938; 12691820)

 

 

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