BMI1 Monoclonal antibody proteintech 66161-1-Ig

$449.00
In stock
SKU
66161-1-Ig

 

RNF51, Polycomb group RING finger protein 4, Polycomb complex protein BMI-1, PCGF4, 2E10A11

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: human, mouse, monkey Immunogen: CatNo: Ag21284 Product name: Recombinant human BMI1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-326 aa of BC011652 Sequence: MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 37 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC011652
Conjugate: Unconjugated Gene Symbol: BMI1
Tested Applications: Positive WB detected in Gene ID (NCBI): 648
Application: Western Blot (WB) RRID: AB_2881557
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Monkey Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody reacts with the 37kd BMI1 protein.

 

 

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