MRP1 Monoclonal antibody proteintech 67228-1-Ig

$449.00
In stock
SKU
67228-1-Ig

 

ABCC1, 1G4A2, MRP1/ABCC1

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Human And More (1) Immunogen: CatNo: Ag27048 Product name: Recombinant human ABCC1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 918-1025 aa of NM_004996 Sequence: SSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGIS Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 172 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM_004996
Conjugate: Unconjugated Gene Symbol: MRP1
Tested Applications: Positive WB detected in Gene ID (NCBI): 4363
Application: Western Blot (WB) RRID: AB_2882516
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: Multidrug resistant-associated protein 1 (MRP1; ABCC1) is a member of the ATP-binding cassette (ABC) transporter protein superfamily, subfamily C. MRP1 is overexpressed in cancers and contributes to the occurrence of multidrug resistance (MDR). Expression of MRP1 has been considered as a negative marker for the outcome of chemotherapy. Recently MRP1 has been reported to play a crucial role in Aβ clearance at the blood-brain barrier.

 

 

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