CD38 Monoclonal antibody proteintech 60006-1-Ig
$449.00
In stock
SKU
60006-1-Ig
2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, 3C6G4, ADP ribosyl cyclase 1
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human, Mouse And More (1) | Immunogen: CatNo: Ag0487 Product name: Recombinant human CD38 protein Source: e coli.-derived, PKG Tag: GST Domain: 1-300 aa of BC007964 Sequence: MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI Predict reactive species |
| Applications: WB, IF/ICC, IF-P, ELISA, Cell treatment | Observed Molecular Weight: 300 aa, 34 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC007964 |
| Conjugate: Unconjugated | Gene Symbol: CD38 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 952 |
| Application: Western Blot (WB) | RRID: ENSG00000004468 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: AB_716994 |
| Tested Reactivity: Human, Mouse | Form: Unconjugated |
| Host / Isotype: Mouse / IgG1 | Background Information: CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500). |
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