Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5) proteintech 65140-1-Ig
$60.00
In stock
SKU
65140-1-Ig
Gr-1, Ly6g, Ly 6G, Ly-6G, Ly-6G.1
| Host / Isotype: Rat / IgG2b, kappa | Class: Monoclonal |
| Reactivity: mouse | Immunogen: Raised against granulocytes of mouse origin Predict reactive species |
| Applications: WB, FC | Observed Molecular Weight: X70920 |
| Formulation: PBS, Azide | GenBank Accession Number: 546644 |
| Conjugate: Unconjugated | Gene Symbol: AB_2881475 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.5 ug per 10^6 cells in 100 μl suspension | Conjugate: Affinity purification |
| Tested Reactivity: Mouse | Form: P35461 |
| Host / Isotype: Rat / IgG2b, kappa | Background Information: Ly-6G (lymphocyte antigen 6 complex, locus G), also known as Gr-1, is a 21-25 kDa, glycosylphosphatidylinositol-anchored protein expressed on myeloid lineage cells in mouse bone marrow (PMID: 8360469). The expression of Ly-6G increases on neutrophils as they differentiate from immature cells in the bone marrow to mature cells in the blood and spleen (PMID: 8890901). Antibodies targeting Ly6G (RB6-8C5 or 1A8) are commonly used in studies aimed at identifying the role of neutrophils (PMID: 23543767). The RB6-8C5 mAb has been reported to cross-react with Ly-6C on cells expressing Ly-6C (PMID: 8360469). |
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