Integrin Alpha 3 Monoclonal antibody proteintech 66070-1-Ig

$449.00
In stock
SKU
66070-1-Ig

 

CD49C, FRP 2, Galactoprotein B3, GAP B3, GAPB3, Integrin alpha 3, ITGA3, MSK18, VCA 2, VL3A, VLA 3 subunit alpha, VLA3a

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human, Pig, Mouse And More (1) Immunogen: CatNo: Ag17293 Product name: Recombinant human Integrin alpha-3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 52-376 aa of BC150190 Sequence: FGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASI Predict reactive species
 Applications: WB, IHC, IF, IP, ELISA Observed Molecular Weight: 1066 aa, 119 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC150190
Conjugate: Unconjugated Gene Symbol: Integrin alpha 3
Tested Applications: Positive WB detected in Gene ID (NCBI): 3675
Application: Western Blot (WB) RRID: AB_11042765
Dilution: WB : 1:500-1:2000 Conjugate: Unconjugated
Tested Reactivity: Human, Pig, Mouse Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: ITGA3, also named as MSK18, CD49c, GAPB3 and FRP-2, belongs to the integrin alpha chain family. It is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain.

 

 

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