ACC1 Monoclonal antibody proteintech 67373-1-Ig

$449.00
In stock
SKU
67373-1-Ig

 

ACACA, ACC-alpha, ACCA, ACC, ACAC

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human, Mouse, Rat And More (3) Immunogen: CatNo: Ag17503 Product name: Recombinant human ACC protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 2260-2383 aa of BC137287 Sequence: LLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 2383 aa, 275 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC137287
Conjugate: Unconjugated Gene Symbol: Acetyl-CoA Carboxylase 1
Tested Applications: Positive WB detected in Gene ID (NCBI): 31
Application: Western Blot (WB) RRID: AB_2882621
Dilution: WB : 1:10000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

 

 

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