TMEM173/STING Monoclonal antibody proteintech 66680-1-Ig
$449.00
In stock
SKU
66680-1-Ig
STING, NET23, MPYS, MITA, ERIS
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, rat | Immunogen: CatNo: Ag20363 Product name: Recombinant human TMEM173 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 174-379 aa of BC047779 Sequence: ELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENGQRAGTCVLEYATPLQTLFAMSQYSQAGFSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTSTMSQEPELLISGMEKPLPLRTDFS Predict reactive species |
| Applications: WB, IHC, IF-P, IP, ELISA | Observed Molecular Weight: 379 aa, 42 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC047779 |
| Conjugate: Unconjugated | Gene Symbol: STING |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 340061 |
| Application: Western Blot (WB) | RRID: AB_2882034 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines. STING is a 379 amino acid protein with a calculated molecular weight of 42 kDa. It has been observed at 35-40 kDa (PMID: 27324217; 29632140; 30918080), and 70-80 kDa corresponding to the expected size of a STING dimer (PMID: 25790474; 29491158). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
