VE-cadherin/CD144 Monoclonal antibody proteintech 66804-1-Ig
$449.00
In stock
SKU
66804-1-Ig
VE-cadherin, 4F9B10, 7B4, 7B4 antigen, Cadherin 5
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag27501 Product name: Recombinant human CDH5 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 54-241 aa of NM_001795 Sequence: MHIDEEKNTSLPHHVGKIKSSVSRKNAKYLLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGT Predict reactive species |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 88 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_001795 |
| Conjugate: Unconjugated | Gene Symbol: VE-cadherin |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1003 |
| Application: Western Blot (WB) | RRID: AB_2882147 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Vascular endothelial cadherin (VE-cadherin), also known as Cadherin-5 (CDH5) or CD144, is a member of the type II classical cadherin family of cell adhesion proteins (PMID: 21269602). VE-cadherin is expressed specifically in endothelial cells and mediates homophilic adhesion in the vascular endothelium (PMID: 1522121; 8555485; 21269602). VE-cadherin plays a role in the organization of lateral endothelial junctions and in the control of permeability properties of vascular endothelium (PMID: 1522121). VE-cadherin has also been shown to be required for angiogenesis (PMID: 16473763; 18162609). |
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