GATM Monoclonal antibody proteintech 68513-1-Ig
$449.00
In stock
SKU
68513-1-Ig
Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5
| Host / Isotype: Mouse / IgG1 | Class: Antibody |
| Reactivity: human, mouse, rat, pig | Immunogen: glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| Applications: WB, ELISA | Observed Molecular Weight: 48 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: GATM |
| Conjugate: Unconjugated | Gene Symbol: 2628 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3085222 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat, Pig | Form: Protein G purification |
| Host / Isotype: Monoclonal | Background Information: GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa. |