GATM Monoclonal antibody proteintech 68513-1-Ig

$449.00
In stock
SKU
68513-1-Ig

 

Transamidinase, L-arginine:glycine amidinotransferase, EC:2.1.4.1, AGAT, 1D12G5

Host / Isotype: Mouse / IgG1 Class: Antibody
Reactivity: human, mouse, rat, pig Immunogen: glycine amidinotransferase (L-arginine:glycine amidinotransferase)
 Applications: WB, ELISA Observed Molecular Weight: 48 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: GATM
Conjugate: Unconjugated Gene Symbol: 2628
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3085222
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human, Mouse, Rat, Pig Form: Protein G purification
Host / Isotype: Monoclonal Background Information: GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa.

 

 

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