ENPP2 Monoclonal antibody proteintech 68724-1-Ig

$449.00
In stock
SKU
68724-1-Ig

 

AUTOTAXIN, E-NPP 2, EC:3.1.4.39, E NPP 2, ATX X

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human, mouse, rat, pig, rabbit Immunogen: CatNo: Ag5499 Product name: Recombinant human ENPP2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 30-383 aa of BC034961 Sequence: AHRIKRAEGWEEGPPTVLSDSPWTNISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDI Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 99 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC034961
Conjugate: Unconjugated Gene Symbol: ENPP2
Tested Applications: Positive WB detected in Gene ID (NCBI): 5168
Application: Western Blot (WB) RRID: AB_3670416
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig, Rabbit Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: ENPP2, Autotaxin or Extracellular lysophospholipase D, is a 863 amino acid secreted protein, which is detected in blood plasma (at protein level) (PubMed:12176993, PubMed:26371182). ENPP2 is Predominantly expressed in brain, placenta, ovary, and small intestine. ENPP2 is expressed in a number of carcinomas such as hepatocellular and prostate carcinoma, neuroblastoma and non-small-cell lung cancer. ENPP2 is expressed in body fluids such as plasma, cerebral spinal fluid (CSF), saliva, follicular and amniotic fluids. The calculated molecular weight of ENPP2 is about 100 kDa (PMID: 22301782), but modified ENPP2 is 120 kDa (PMID: 19808661). ENPP2 Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751, PubMed:26371182, PubMed:27754931).

 

 

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