TMEM175 Monoclonal antibody proteintech 68172-1-Ig
$449.00
In stock
SKU
68172-1-Ig
1E7E1, hTMEM175, Transmembrane protein 175
| Host / Isotype: Mouse / IgG1 | Class: Antibody |
| Reactivity: human, mouse, rat, pig, rabbit | Immunogen: transmembrane protein 175 |
| Applications: WB, IP, ELISA | Observed Molecular Weight: 55-60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TMEM175 |
| Conjugate: Unconjugated | Gene Symbol: 84286 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2923687 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat, Pig, Rabbit | Form: Protein G purification |
| Host / Isotype: Monoclonal | Background Information: TMEM175 has two repeats of 6-transmembrane-spanning segments and has no GYG K+ channel sequence signature-containing, pore-forming P loop. Lysosomes lacking TMEM175 exhibit no K+conductance, have a markedly depolarized ΔΨ and little sensitivity to changes in [K+], and have compromised luminal pH stability and abnormal fusion with autophagosomes during autophagy. TMEM175 comprises a K+ channel that underlies the molecular mechanism of lysosomal K+ permeability. |
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