E2F1 Monoclonal antibody proteintech 66515-1-Ig
$449.00
In stock
SKU
66515-1-Ig
5D7G8, E2F 1, E2F-1, pRB-binding protein E2F-1, RBAP-1
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: Human, Rat And More (1) | Immunogen: CatNo: Ag17363 Product name: Recombinant human E2F1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 88-438 aa of BC050369 Sequence: VKRRLDLETDHQYLAESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF Predict reactive species |
| Applications: WB, IHC, IF, IP, CoIP, ChIP, ELISA | Observed Molecular Weight: 437 aa, 47 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC050369 |
| Conjugate: Unconjugated | Gene Symbol: E2F1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1869 |
| Application: Western Blot (WB) | RRID: AB_2881878 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Transcription factor E2F1 (E2F1), also known as RBBP3, is a transcription activator that binds DNA cooperatively with dp proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-1 binds preferentially RB1 protein, in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent apoptosis. The calculated molecular weight of E2F1 is 47 kDa, but the sumoylated E2F1 is bout 55-60 kDa. |
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