EGFR Monoclonal antibody proteintech 66455-1-Ig
$449.00
In stock
SKU
66455-1-Ig
2A2H10, EGF R, EGF Receptor , Epidermal growth factor receptor, Proto-oncogene c-ErbB-1
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag24947 Product name: Recombinant human EGFR protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 291-534 aa of BC094761 Sequence: VCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNC Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 1210 aa, 134 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC094761 |
| Conjugate: Unconjugated | Gene Symbol: EGFR |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1956 |
| Application: Western Blot (WB) | RRID: AB_2881824 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer. |
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