Ataxin 2 Monoclonal antibody proteintech 68316-1-Ig
$449.00
In stock
SKU
68316-1-Ig
| Host / Isotype: Mouse / IgM | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: ataxin 2 |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 140-150 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: ATXN2 |
| Conjugate: Unconjugated | Gene Symbol: 6311 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3085052 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Caprylic acid/ammonium sulfate precipitation |
| Host / Isotype: Monoclonal | Background Information: ATXN2 contains a repeat structure with 22 or 23 triplets coding for glutamine and the (CAG)8CAA(CAG)4CAA(CAG)8 sequence; expansion of this domain to a size ≥34 triplets with a pure CAG sequence primarily causes autosomal dominant SCA2 [PMID:18418684], while ATXN2 expansions with CAA interruptions were observed as the cause of Levo-dopa responsive Parkinson's disease [PMID:10668726]. ATXN2 expansions associated with ALS were reported to be interrupted by at least one CAA triplet [PMID:21537950] |
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