PYCR1 Monoclonal antibody proteintech 66510-1-Ig
$449.00
In stock
SKU
66510-1-Ig
P5CR 1, P5CR, P5C reductase 1, P5C, EC:1.5.1.2
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag17919 Product name: Recombinant human PYCR1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-171 aa of BC022244 Sequence: MEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD Predict reactive species |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 319 aa, 33.8 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC022244 |
| Conjugate: Unconjugated | Gene Symbol: PYCR1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5831 |
| Application: Western Blot (WB) | RRID: AB_2881873 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: PYCR1,also named as P5CR1, belongs to the pyrroline-5-carboxylate reductase family. It is a housekeeping enzyme that catalyzes the last step in proline biosynthesis. PYCR1 can utilize both NAD and NADP, but has higher affinity for NAD. It is involved in the cellular response to oxidative stress. Mutation in PYCR1 will cause ARCL type II(ARCL2B ). Some mutation will cause DeBarsy syndrome (DBS) which is characterized by progeroid features, ophthalmological abnormalities, intrauterine growth retardation, and cutis laxa. |
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