SMAD3 Monoclonal antibody proteintech 66516-1-Ig

$449.00
In stock
SKU
66516-1-Ig

 

JV15 2, HsT17436, HSPC193, hSMAD3, hMAD-3

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Human, Mouse And More (1) Immunogen: Peptide Predict reactive species
 Applications: WB, IHC, IF, IP, CoIP, ChIP, ELISA Observed Molecular Weight: 48 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM_005902
Conjugate: Unconjugated Gene Symbol: SMAD3
Tested Applications: Positive WB detected in Gene ID (NCBI): 4088
Application: Western Blot (WB) RRID: AB_2881879
Dilution: WB : 1:2000-1:12000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: SMAD3, also named as hMAD 3 or Mad3, is a 425 amino acid protein, which contains one MH1 domain and one MH2 domain. SMAD3 localizes in the nucleus and cytoplasm. SMAD3 plays an essential role in development and maintenance of self-tolerance and is a critical mediator of the TGFB signaling pathway. SMAD3 is involved in TGFB dependent regulation of steroidogenesis and in T-cell response to TGFB.

 

 

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