Galectin-3 Monoclonal antibody proteintech 60207-1-Ig

$449.00
In stock
SKU
60207-1-Ig

 

1C1B2, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, CBP35

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: Human, Mouse And More (1) Immunogen: CatNo: Ag6753 Product name: Recombinant human Galectin 3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-250 aa of BC001120 Sequence: MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, FC (Intra), IP, CoIP, ELISA Observed Molecular Weight: 26 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001120
Conjugate: Unconjugated Gene Symbol: Galectin-3
Tested Applications: Positive WB detected in Gene ID (NCBI): 3958
Application: Western Blot (WB) RRID: AB_10951109
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides (PMID: 8063692). Galectin-3, a member of the β-galactoside-binding proteins, contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers (PMID: 14758078). Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell, being present on the cell surface or in the extracellular space (PMID: 16478649). Galectin-3 is involved in various biological processes including cell growth, adhesion, differentiation, apoptosis, angiogenesis, immune response, neoplastic transformation and metastasis (PMID: 16478649; 14758078).

 

 

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