F4/80 Polyclonal antibody proteintech 28463-1-AP

$449.00
In stock
SKU
28463-1-AP

 

Adgre1, Adhesion G protein-coupled receptor E1, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, Emr1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Mouse, Rat And More (2) Immunogen: CatNo: Ag28252 Product name: Recombinant mouse Adgre1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 443-644 aa of NM_010130 Sequence: MELSKEETSTLGTILLETVESTMLAALLIPSGNASQMIQTEYLDIESKVINEECKENESINLAARGDKMNVGCFIIKESVSTGAPGVAFVSFAHMESVLNERFFEDGQSFRKLRMNSRVVGGTVTGEKKEDFSKPIIYTLQHIQPKQKSERPICVSWNTDVEDGRWTPSGCEIVEASETHTVCSCNRMANLAIIMASGELTME Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, IF-Fro, ELISA Observed Molecular Weight: 102 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM_010130
Conjugate: Unconjugated Gene Symbol: F4/80
Tested Applications: Positive WB detected in Gene ID (NCBI): 13733
Application: Western Blot (WB) RRID: AB_2881149
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Mouse F4/80, also named as EMR1 and Gpf480, is a 160-kDa cell surface glycoprotein which is a member of the EGF TM7 family. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. The function of F4/80 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages.

 

 

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