TLR4 Monoclonal antibody proteintech 66350-1-Ig

$449.00
In stock
SKU
66350-1-Ig

 

3G9A4, ARMD10, CD284, hToll, TOLL

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: Human, Mouse, Rat, Pig And More (3) Immunogen: CatNo: Ag13857 Product name: Recombinant human TLR4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 653-839 aa of BC117422 Sequence: KFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI Predict reactive species
 Applications: WB, IHC, IF, IP, CoIP, ELISA Observed Molecular Weight: 839 aa, 96 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC117422
Conjugate: Unconjugated Gene Symbol: TLR4
Tested Applications: Positive WB detected in Gene ID (NCBI): 7099
Application: Western Blot (WB) RRID: AB_2881730
Dilution: WB : 1:1000-1:8000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: TLR4, also named CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion, and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

 

 

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