TLR4 Monoclonal antibody proteintech 66350-1-Ig
$449.00
In stock
SKU
66350-1-Ig
3G9A4, ARMD10, CD284, hToll, TOLL
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: Human, Mouse, Rat, Pig And More (3) | Immunogen: CatNo: Ag13857 Product name: Recombinant human TLR4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 653-839 aa of BC117422 Sequence: KFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI Predict reactive species |
| Applications: WB, IHC, IF, IP, CoIP, ELISA | Observed Molecular Weight: 839 aa, 96 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC117422 |
| Conjugate: Unconjugated | Gene Symbol: TLR4 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7099 |
| Application: Western Blot (WB) | RRID: AB_2881730 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Pig | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: TLR4, also named CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion, and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |