Bcl2 Monoclonal antibody proteintech 68103-1-Ig

$449.00
In stock
SKU
68103-1-Ig

 

Bcl-2, 1B3F7, B cell leukemia/lymphoma 2, Bcl 2

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Mouse, Rat And More (3) Immunogen: CatNo: Ag24261 Product name: Recombinant mouse Bcl2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-236 aa of NM-009741 Sequence: MAQAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDADAAPLGAAPTPGIFSFQPESNPMPAVHRDMAARTSPLRPLVATAGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 26 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM-009741
Conjugate: Unconjugated Gene Symbol: Bcl2
Tested Applications: Positive WB detected in Gene ID (NCBI): 12043
Application: Western Blot (WB) RRID: AB_2923635
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: Bcl2 is a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues.

 

 

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