SIRP Alpha/CD172a Monoclonal antibody proteintech 67337-1-Ig
$449.00
In stock
SKU
67337-1-Ig
SIRP Alpha, SIRPA, 2F8H3, BIT, Brain Ig-like molecule with tyrosine-based activation motifs
| Host / Isotype: Mouse / IgG2b | Class: Antibody |
| Reactivity: human, mouse, rat, pig, rabbit | Immunogen: signal-regulatory protein alpha |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 75-85 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SIRP Alpha |
| Conjugate: Unconjugated | Gene Symbol: 140885 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2882595 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat, Pig, Rabbit | Form: Protein A purification |
| Host / Isotype: Monoclonal | Background Information: SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID:?36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954). This antibody detects a 75-85 kDa band. |
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