Integrin alpha 4 Monoclonal antibody proteintech 67040-1-Ig

$449.00
In stock
SKU
67040-1-Ig

 

ITGA4, 1B6A3, CD49 antigen-like family member D, CD49D, IA4

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human Immunogen: CatNo: Ag28024 Product name: Recombinant human Integrin alpha-4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 653-1032 aa of BC156712 Sequence: SMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYINSKSNDD Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 1032 aa, 115 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC156712
Conjugate: Unconjugated Gene Symbol: Integrin alpha 4
Tested Applications: Positive WB detected in Gene ID (NCBI): 3676
Application: Western Blot (WB) RRID: AB_2882354
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: Integrin alpha 4 (ITGA4), also named CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1, and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

 

 

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