Integrin alpha 4 Monoclonal antibody proteintech 67040-1-Ig
$449.00
In stock
SKU
67040-1-Ig
ITGA4, 1B6A3, CD49 antigen-like family member D, CD49D, IA4
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag28024 Product name: Recombinant human Integrin alpha-4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 653-1032 aa of BC156712 Sequence: SMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEENRRDSWSYINSKSNDD Predict reactive species |
| Applications: WB, ELISA | Observed Molecular Weight: 1032 aa, 115 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC156712 |
| Conjugate: Unconjugated | Gene Symbol: Integrin alpha 4 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3676 |
| Application: Western Blot (WB) | RRID: AB_2882354 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: Integrin alpha 4 (ITGA4), also named CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1, and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. |