Integrin alpha 4 Polyclonal antibody proteintech 19676-1-AP
$449.00
In stock
SKU
19676-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (2) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 115 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_000885 |
| Conjugate: Unconjugated | Gene Symbol: Integrin alpha 4 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3676 |
| Application: Western Blot (WB) | RRID: AB_10640907 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Integrin alpha 4 (ITGA4), also named CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1, and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. |
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