CDO1 Polyclonal antibody proteintech 12589-1-AP
$449.00
In stock
SKU
12589-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat, pig | Immunogen: CatNo: Ag3294 Product name: Recombinant human CDO1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-200 aa of BC024241 Sequence: MEQTEVLKPRTLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYRYTRNLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSVGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTPNATSGSLENN Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, ELISA | Observed Molecular Weight: 200 aa, 23 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC024241 |
| Conjugate: Unconjugated | Gene Symbol: CDO1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1036 |
| Application: Western Blot (WB) | RRID: AB_10638145 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Pig | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid (3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase (CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO (23?kDa, 25?kDa, and 68?kDa) have been claimed based upon separation and detection using SDS-PAGE/western blotting(PMID: 14752623). |
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