TRIF/TICAM1 Polyclonal antibody proteintech 23288-1-AP
$449.00
In stock
SKU
23288-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (3) | Immunogen: CatNo: Ag19779 Product name: Recombinant human TICAM1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-200 aa of BC035331 Sequence: LDEHSQIFARKVANTFKPHRLQARKAMWRKEQDTRALREQSQHLDGERMQAAALNAAYSAYLQSYLSYQAQMEQLQVAFGSHMSFGTGAPYGARMPFGGQVPLGAPPPFPTWPGCPQPPPLHAWQAGTPPPPSPQPAAFPQSLPFPQSPAFPTASPAPPQSPGLQPLIIHHAQMVQLGLNNHMWNQRGSQAPEDKTQEAE Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 712 aa, 76 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC035331 |
| Conjugate: Unconjugated | Gene Symbol: TRIF |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 148022 |
| Application: Western Blot (WB) | RRID: AB_2879247 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: TRIF (adaptor-induced interferon-β containing the tir domain) is a key adapter protein in Toll-like receptor signaling, mediating the MyD88-independent pathway of TLR3 and TLR4. It activates NF-κB and interferon regulator 3 (IRF3), leading to the production of type I interferon and pro-inflammatory cytokines. TRIF recruits TRAF3 to activate TBK1/IKKε kinases and interacts with RIPK1, playing a crucial dual role in antiviral and inflammatory innate immune responses.(PMID: 12855817; 14519765; 28469251) |
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