AGGF1 Polyclonal antibody proteintech 11889-1-AP

$449.00
In stock
SKU
11889-1-AP

 

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (3) Immunogen: CatNo: Ag2497 Product name: Recombinant human AGGF1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 4-270 aa of BC029382 Sequence: DMEHTLRIPEVGVSKFHAEIYFDHDLQSYVPVDQGSQNGTIVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKKDESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMP Predict reactive species
 Applications: WB, IHC, IF, IP, ELISA Observed Molecular Weight: 714 aa, 81 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC029382
Conjugate: Unconjugated Gene Symbol: AGGF1
Tested Applications: Positive WB detected in Gene ID (NCBI): 55109
Application: Western Blot (WB) RRID: AB_2305338
Dilution: WB : 1:1000-1:8000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.

 

 

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