Phospho-STAT3 (Ser727) Polyclonal antibody proteintech 28945-1-AP
$449.00
In stock
SKU
28945-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (3) | Immunogen: Peptide Predict reactive species |
| Applications: WB, IF, ELISA | Observed Molecular Weight: 770 aa, 88 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000627 |
| Conjugate: Unconjugated | Gene Symbol: STAT3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6774 |
| Application: Western Blot (WB) | RRID: AB_3206262 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3, synonyms: APRF, FLJ20882, MGC16063) is a member of the STAT protein family. Phosphorylated STAT3 dimerizes and translocates to the nucleus, where it regulates the transcription of target genes through binding to specific DNA-responsive elements. In addition to activation by Tyr705 phosphorylation, STAT3 also requires phosphorylation on Ser727 to achieve maximal transcriptional activity. (PMID: 21617181) |
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