BAK Polyclonal antibody proteintech 29552-1-AP

$449.00
In stock
SKU
29552-1-AP

 

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (1) Immunogen: CatNo: Ag31042 Product name: Recombinant human BAK protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-100 aa of NM_001188 Sequence: MASGQGPGPPRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHL Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 23 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM_001188
Conjugate: Unconjugated Gene Symbol: BAK1
Tested Applications: Positive WB detected in Gene ID (NCBI): 578
Application: Western Blot (WB) RRID: AB_2923596
Dilution: WB : 1:2000-1:12000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

 

 

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