FOXA2 Polyclonal antibody proteintech 22474-1-AP
$449.00
In stock
SKU
22474-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag18221 Product name: Recombinant human FOXA2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-160 aa of BC011780 Sequence: MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKP Predict reactive species |
| Applications: WB, IHC, IF-P, IP, CoIP, chIP, ELISA | Observed Molecular Weight: 457 aa, 48 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC011780 |
| Conjugate: Unconjugated | Gene Symbol: FOXA2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3170 |
| Application: Western Blot (WB) | RRID: AB_2879110 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: FOXA2 also named as HNF 3 beta or TCF3B is a 457 amino acid protein, which contains one fork-head DNA-binding domains. FOXA2 can Shuttle between the nucleus and cytoplasm in a CRM1-dependent manner. Phosphorylation on FOXA2 Thr-156 abolishes binding to target promoters and subsequent transcription activation upon INS stimulation. FOXA2 as a transcription factor involves in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. The molecular weight of FOXA2 is 48kDa, but the phosphorylated FOXA2 may be a 55-65kDa protein. |
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