Drebrin Polyclonal antibody proteintech 10260-1-AP
$449.00
In stock
SKU
10260-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse And More (1) | Immunogen: CatNo: Ag0371 Product name: Recombinant human Drebrin protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 118-302 aa of BC000283 Sequence: ASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERVAS Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, ELISA | Observed Molecular Weight: 71 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000283 |
| Conjugate: Unconjugated | Gene Symbol: Drebrin |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1627 |
| Application: Western Blot (WB) | RRID: ENSG00000113758 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: AB_2230301 |
| Tested Reactivity: Human, Mouse | Form: Unconjugated |
| Host / Isotype: Rabbit / IgG | Background Information: Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients. |
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