HSP90 Polyclonal antibody proteintech 13171-1-AP
$449.00
In stock
SKU
13171-1-AP
HSP90AA1, EC:3.6.4.10, Heat shock protein family C member 1, Heat shock protein HSP 90 alpha, Heat shock protein HSP 90-alpha
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (7) | Immunogen: CatNo: Ag3826 Product name: Recombinant human HSP90 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 287-638 aa of BC023006 Sequence: YLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), IP, CoIP, RIP, ELISA | Observed Molecular Weight: 853 aa, 90 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC023006 |
| Conjugate: Unconjugated | Gene Symbol: HSP90 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 3320 |
| Application: Western Blot (WB) | RRID: AB_2120924 |
| Dilution: WB : 1:2000-1:16000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application. This antibody may cross-react with HSP90AB1 due to the high homology between them. |
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