BCAT2 Polyclonal antibody proteintech 16417-1-AP

$449.00
In stock
SKU
16417-1-AP

 

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse And More (1) Immunogen: CatNo: Ag9573 Product name: Recombinant human BCAT2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 41-392 aa of BC001900 Sequence: MTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV Predict reactive species
 Applications: WB, IHC, IF/ICC, FC (Intra), ELISA Observed Molecular Weight: 44 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001900
Conjugate: Unconjugated Gene Symbol: BCAT2
Tested Applications: Positive WB detected in Gene ID (NCBI): 587
Application: Western Blot (WB) RRID: AB_10792411
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: Branched-chain amino acid transaminase 2 (BCAT2) is an important enzyme in branched-chain amino acids (BCAAs) catabolism that reversibly catalyzes the initial step of BCAA degradation to branched-chain acyl-CoA. In humans, BCAT2 encodes a mitochondrial protein that is ubiquitously expressed in all organs (except hepatocytes) (PMID:32467562). Moreover, other reports showed that overexpressed BCAT2 in pancreatic ductal adenocarcinoma (PDAC) cells enhanced cell proliferation and survival in vitro and in vivo (PMID:35663242).

 

 

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