RYR2 Polyclonal antibody proteintech 19765-1-AP
$449.00
In stock
SKU
19765-1-AP
ARVC2, ARVD2, Cardiac muscle ryanodine receptor-calcium release channel, hRYR-2, ryanodine receptor 2 (cardiac)
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, mouse, rat | Immunogen: Peptide Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, ELISA | Observed Molecular Weight: 565 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_001035 |
| Conjugate: Unconjugated | Gene Symbol: RYR2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6262 |
| Application: Western Blot (WB) | RRID: AB_10637859 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: RYR2 belongs to the ryanodine receptor family. RYR2 provides communication between transverse-tubules and sarcoplasmic reticulum. Contraction of cardiac muscle is triggered by release of calcium ions from SR following depolarization of T-tubules. Defects in RYR2 are the cause of familial arrhythmogenic right ventricular dysplasia type 2 (ARVD2) which known as arrhythmogenic right ventricular cardiomyopathy 2 (ARVC2). Defects in RYR2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) which known as stress-induced polymorphic ventricular tachycardia (VTSIP). This antibody detects a band at ~250 kDa which has been reported (PMID: 22962011). |
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