SIX1 Polyclonal antibody proteintech 10709-1-AP

$449.00
In stock
SKU
10709-1-AP

 

BOS3, DFNA23, Homeobox protein SIX1, Sine oculis homeobox homolog 1, SIX homeobox 1

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse And More (1) Immunogen: CatNo: Ag1044 Product name: Recombinant human SIX1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-284 aa of BC008874 Sequence: MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLCGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGHARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGS Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, CoIP, RIP, ELISA Observed Molecular Weight: 32 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC008874
Conjugate: Unconjugated Gene Symbol: SIX1
Tested Applications: Positive WB detected in Gene ID (NCBI): 6495
Application: Western Blot (WB) RRID: AB_2189077
Dilution: WB : 1:500-1:1000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: SIX1 belongs to SIX family that contains a divergent DNA-binding homeodomain and an upstream SIX domain, which may participate both in determining DNA-binding specificity and in mediating protein-protein interactions. It may be involved in limb tendon and ligament development, and specifically expressed in skeletal muscle. SIX1 plays a essential role in the development of numerous organs and shows littlt to no expression in most non-neoplastic adult tissue, yet is overexpression in a number of meoplasms where it increases cell proliferation and survival. The calcualted molecular weight of SIX1 is 32kDa, but modified SIX1 is about 35 kDa.

 

 

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