Anti-Human IL-10 (7B8G3) Proteintech 65286-1-Ig
$299.00
In stock
SKU
65286-1-Ig
IL-10,IL10, 7B8G3, CSIF, IL 10, IL10
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) (INTRA) | Formulation::PBS, Azide2 |
| Reactivity:Mouse / IgG2b | Formulation::PBS, Azide3 |
| Type:CatNo: Product name: HumanKine? recombinant human IL-10 protein Source: -derived, Tag: Domain: of Sequence: Predict reactive species | Formulation::PBS, Azide4 |
| RRID:3586 | Formulation::PBS, Azide5 |
| Storage Buffer:P22301 | Formulation::PBS, Azide6 |
| Background Information:Interleukin (IL)-10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC) (INTRA)0 |