CoraLite? Plus 647 Anti-Human CD80 (2D10.4) Proteintech CL647-65083
$299.00
In stock
SKU
CL647-65083
2D10.4, Activation B7 1 antigen, Activation B7-1 antigen, B7, B7 1
| Formulation::PBS, Azide, BSA | Formulation::PBS, Azide, BSA1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide, BSA2 |
| Reactivity:Mouse / IgG1, kappa | Formulation::PBS, Azide, BSA3 |
| Type:N/A Predict reactive species | Formulation::PBS, Azide, BSA4 |
| RRID:941 | Formulation::PBS, Azide, BSA5 |
| Storage Buffer:Liquid | Formulation::PBS, Azide, BSA6 |
| Background Information:CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215) | Formulation::PBS, Azide, BSA7 |
| biogegep8 | Formulation::PBS, Azide, BSA8 |
| biogegep9 | Formulation::PBS, Azide, BSA9 |
| Formulation::PBS, Azide, BSA0 | Applications:Flow Cytometry (FC)0 |