Anti-Human CD45RB/RAB Rabbit Recombinant Antibody Proteintech 98531-5-RR
$299.00
In stock
SKU
98531-5-RR
CD45, CD45RAB, CD45RB, EC:3.1.3.48, GP180
| Formulation:：PBS, Azide | Formulation:：PBS, Azide1 |
| Applications：Flow Cytometry (FC) | Formulation:：PBS, Azide2 |
| Reactivity：Rabbit / IgG | Formulation:：PBS, Azide3 |
| Type：Peptide Predict reactive species | Formulation:：PBS, Azide4 |
| RRID：5788 | Formulation:：PBS, Azide5 |
| Storage Buffer：Protein A purification | Formulation:：PBS, Azide6 |
| Background Information：CD45RB and CD45RAB are specific isoforms of CD45, a receptor-type protein tyrosine phosphatase (PTP) found on the surface of all nucleated hematopoietic cells, except mature erythrocytes and platelets. They serve as essential phenotypic markers to distinguish na?ve T lymphocytes from antigen-experienced memory/effector T cells. CD45RB and CD45RAB designations refer to specific isoforms of CD45 generated through alternative splicing of three variable exons (4, 5, and 6) in the PTPRC gene. These exons encode extracellular domains A, B, and C, respectively, which contain O-linked glycosylation sites that affect the molecule's size, charge, and ligand-binding properties. This antibody can detect CD45RB (contains exons B only) and CD45RAB (contains both exons A and B), but not CD45RABC (contain all three exons) or CD45RBC (contain exons B and C). | Formulation:：PBS, Azide7 |
| biogegep8 | Formulation:：PBS, Azide8 |
| biogegep9 | Formulation:：PBS, Azide9 |
| Formulation:：PBS, Azide0 | Applications：Flow Cytometry (FC)0 |
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