Anti-Human CD163 (GHI/61) Proteintech 65169-1-Ig
$299.00
In stock
SKU
65169-1-Ig
CD163, CD163 molecule, Hemoglobin scavenger receptor, M130, MM130, sCD163
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide2 |
| Reactivity:Mouse / IgG1, kappa | Formulation::PBS, Azide3 |
| Type:Glycoprotein preparation from hairy cell leukemia spleen Predict reactive species | Formulation::PBS, Azide4 |
| RRID:9332 | Formulation::PBS, Azide5 |
| Storage Buffer:Liquid | Formulation::PBS, Azide6 |
| Background Information:CD163, also known as M130, is a membrane glycoprotein which belongs to the scavenger receptor superfamily (PMID: 8370408). It is an acute phase-regulated and signal-inducing macrophage protein expressed exclusively in monocytes and tissue macrophages (PMID: 11196644). CD163 mediates endocytosis of haptoglobin-haemoglobin complexes (PMID: 11196644). The uptake of haptoglobin by macrophages contributes to the recycling of iron and also to the inflammatory response (PMID: 22900885). Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity (PMID: 12570164). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Flow Cytometry (FC)0 |