Anti-Mouse CD8a (53-6.7) Proteintech 65069-1-Ig
$299.00
In stock
SKU
65069-1-Ig
CD8, 53-6.7, CD8 antigen, alpha chain, CD8α, Ly 2
| Formulation:：PBS, Azide | Formulation:：PBS, Azide1 |
| Applications：Immunofluorescence (IF)-P | Formulation:：PBS, Azide2 |
| Reactivity：Mouse | Formulation:：PBS, Azide3 |
| Type：Antibody | Formulation:：PBS, Azide4 |
| RRID：12525 | Formulation:：PBS, Azide5 |
| Storage Buffer：Protein G purification | Formulation:：PBS, Azide6 |
| Background Information：CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer, while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). | Formulation:：PBS, Azide7 |
| biogegep8 | Formulation:：PBS, Azide8 |
| biogegep9 | Formulation:：PBS, Azide9 |
| Formulation:：PBS, Azide0 | Applications：Immunofluorescence (IF)-P0 |
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