Anti-Mouse CD107a / LAMP1 (1D4B) Proteintech 65050-1-Ig
$299.00
In stock
SKU
65050-1-Ig
CD107a, Lamp1, 1D4B, Lamp 1
| Formulation::PBS, Azide | Formulation::PBS, Azide1 |
| Applications:Immunofluorescence (IF)/ICC | Formulation::PBS, Azide2 |
| Reactivity:Mouse | Formulation::PBS, Azide3 |
| Type:Antibody | Formulation::PBS, Azide4 |
| RRID:16783 | Formulation::PBS, Azide5 |
| Storage Buffer:Protein G purification | Formulation::PBS, Azide6 |
| Background Information:LAMP1 (CD107a) is a heavily glycosylated membrane protein enriched in the lysosomal membrane. LAMP1 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP1 is expressed largely in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane (PMID: 16168398). Elevated LAMP1 expression at the cell surface has also been detected during platelet and granulocytic cell activation, as well as in some tumor cells (PMID: 29085473). LAMP1 functions to provide selectins with carbohydrate ligands. This protein has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis (PMID: 18835598; 29085473; 9426697). | Formulation::PBS, Azide7 |
| biogegep8 | Formulation::PBS, Azide8 |
| biogegep9 | Formulation::PBS, Azide9 |
| Formulation::PBS, Azide0 | Applications:Immunofluorescence (IF)/ICC0 |