FcZero-rAb? APC Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2) Rabbit IgG Recombinant Antibody Proteintech APC-FcA65663

$299.00
In stock
SKU
APC-FcA65663

 

H2Aa, Aalpha, H 2Aa, H2-Aa, Ia 1

Formulation::PBS, Azide, BSA Formulation::PBS, Azide, BSA1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide, BSA2
 Reactivity:Rabbit / IgG Formulation::PBS, Azide, BSA3
Type:N/A Predict reactive species Formulation::PBS, Azide, BSA4
RRID:APC Fluorescent Dye Formulation::PBS, Azide, BSA5
Storage Buffer:P14434 Formulation::PBS, Azide, BSA6
Background Information:Major histocompatibility complex (MHC) class II molecules are heterodimeric transmembrane glycoproteins that are expressed on the surface of antigen-presenting cells such as dendritic cells, macrophages, and B cells. The M5/114.15.2 antibody detects polymorphic determinants present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2b, H-2d, H-2q, H-2p, H-2r and H-2u haplotypes but not from mice carrying the H-2s or H-2f haplotypes (PMID: 6170707). This antibody recognizes both I-A and I-E subregion-encoded Ia glycoproteins (I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, not I-Af, I-Ak, or I-As). M5/114 antibody is reported to inhibit I-A subregion-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not the H-2f, H-2k, H-2s haplotypes (PMID: 6173436). Formulation::PBS, Azide, BSA7
biogegep8 Formulation::PBS, Azide, BSA8
biogegep9 Formulation::PBS, Azide, BSA9
Formulation::PBS, Azide, BSA0 Applications:Flow Cytometry (FC)0

 

 

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