FcZero-rAb? PE Anti-Mouse IL-13RA2 Rabbit Recombinant Antibody Proteintech PE-FcA98407-3

$299.00
In stock
SKU
PE-FcA98407-3

 

CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2

Formulation::PBS, Azide, BSA Formulation::PBS, Azide, BSA1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide, BSA2
 Reactivity:Rabbit / IgG Formulation::PBS, Azide, BSA3
Type:CatNo: Eg3118 Product name: Recombinant Mouse IL-13RA2 protein (rFc Tag) (HPLC verified) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 22-334 aa of NM_008356.4 Sequence: LEIKVNPPQDFEILDPGLLGYLYLQWKPPVVIEKFKGCTLEYELKYRNVDSDSWKTIITRNLIYKDGFDLNKGIEGKIRTHLSEHCTNGSEVQSPWIEASYGISDEGSLETKIQDMKCIYYNWQYLVCSWKPGKTVYSDTNYTMFFWYEGLDHALQCADYLQHDEKNVGCKLSNLDSSDYKDFFICVNGSSKLEPIRSSYTVFQLQNIVKPLPPEFLHISVENSIDIRMKWSTPGGPIPPRCYTYEIVIREDDISWESATDKNDMKLKRRANESEDLCFFVRCKVNIYCADDGIWSEWSEEECWEGYTGPDSK Predict reactive species Formulation::PBS, Azide, BSA4
RRID:16165 Formulation::PBS, Azide, BSA5
Storage Buffer:Protein A purification Formulation::PBS, Azide, BSA6
Background Information:IL-13RA2, also named as IL-13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). IL-13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL-13RA2 gene polymorphisms have been associated with systemic sclerosis (PMID: 16981293). Overexpression of IL-13RA2 gene has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target (PMID: 19895199; 24970476; 24021875). Formulation::PBS, Azide, BSA7
biogegep8 Formulation::PBS, Azide, BSA8
biogegep9 Formulation::PBS, Azide, BSA9
Formulation::PBS, Azide, BSA0 Applications:Flow Cytometry (FC)0

 

 

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