FcZero-rAb? APC Anti-Human CD8a (OKT8) Rabbit IgG Recombinant Antibody Proteintech APC-FcA65506
$299.00
In stock
SKU
APC-FcA65506
CD8, p32, OKT8, MAL, Leu2
| Formulation::PBS, Azide, BSA | Formulation::PBS, Azide, BSA1 |
| Applications:Flow Cytometry (FC) | Formulation::PBS, Azide, BSA2 |
| Reactivity:Rabbit / IgG | Formulation::PBS, Azide, BSA3 |
| Type:Human thymocytes Predict reactive species | Formulation::PBS, Azide, BSA4 |
| RRID:925 | Formulation::PBS, Azide, BSA5 |
| Storage Buffer:Liquid | Formulation::PBS, Azide, BSA6 |
| Background Information:CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells, on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T-cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). | Formulation::PBS, Azide, BSA7 |
| biogegep8 | Formulation::PBS, Azide, BSA8 |
| biogegep9 | Formulation::PBS, Azide, BSA9 |
| Formulation::PBS, Azide, BSA0 | Applications:Flow Cytometry (FC)0 |