Anti-Mouse uPAR/CD87 Rabbit Recombinant Antibody Proteintech 98424-3-RR

$299.00
In stock
SKU
98424-3-RR

 

CD87, Plaur, uPAR, U-PAR, Urokinase plasminogen activator surface receptor

Formulation::PBS, Azide Formulation::PBS, Azide1
Applications:Flow Cytometry (FC) Formulation::PBS, Azide2
 Reactivity:Rabbit / IgG Formulation::PBS, Azide3
Type:CatNo: Eg3156 Product name: Recombinant Mouse uPAR/CD87 protein (rFc Tag) Source: mammalian cells-derived, V37 Tag: C-rFc Domain: 24-297 aa of NM_011113.4 Sequence: LQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPRPGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSNQTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCATASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPT Predict reactive species Formulation::PBS, Azide4
RRID:18793 Formulation::PBS, Azide5
Storage Buffer:P35456 Formulation::PBS, Azide6
Background Information:uPAR, also known as CD87, is a highly glycosylated, GPI-anchored membrane protein. In addition to the membrane-anchored form, uPAR is released from the plasma membrane by cleavage of the GPI anchor and can be found as a soluble form (suPAR). uPAR contains three homologous domains (D1-D3) of which the N-terminal one (D1) represents the uPA-binding domain. After binding to uPAR, uPA cleaves plasminogen, generating the active protease plasmin which is involved in a wide variety of physiologic and pathologic processes. In addition to regulating proteolysis, uPAR has important function in cell adhesion, migration and proliferation. Studies reveal that uPAR expression is elevated during inflammation and tissue remodeling and in many human cancers, in which it frequently indicates poor prognosis. (PMID 20027185; 12461559) Formulation::PBS, Azide7
biogegep8 Formulation::PBS, Azide8
biogegep9 Formulation::PBS, Azide9
Formulation::PBS, Azide0 Applications:Flow Cytometry (FC)0

 

 

Reviews

Write Your Own Review
You're reviewing:Anti-Mouse uPAR/CD87 Rabbit Recombinant Antibody Proteintech 98424-3-RR
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.